- 11th EuPFI Conference
- Programme
- Preconference Workshop Presentations
- Plenary presentations
- Focus Session Presentations
- Case Study Presentations
- Soapbox Session Presentations
- Posters
- PCCA Award Winners
- EuPFI 2019 Picture Gallery
Hosting Institution
European Paediatric Formulation Initiative in partnership with International Association for Pharmaceutical Technology.
Conference Venue
Preconference workshop venueUniversity College London School of Pharmacy, 29-39 Brunswick Square, London WC1N1AX United Kingdom
Conference venueBMA House, Tavistock Square, London WC1H9JP United Kingdom
Important Dates
| Apr 9thth 2018 | Preliminary programme announcement |
| July 20th2018 | Second announcement |
| Apr 10thth2018 | On-line registration and abstract submission open |
| July 5thth 2018 | Abstract submission deadline for poster presentations only |
| July 3rd2018 | Notification about abstract acceptance (preliminary date) |
Conference Dates
September 12 to 13th 2018
Preconference workshop - 11th September 2018
Programme
EuPFI 2018 Preliminary Programme - Click here
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Plenary Presentations
Paediatric oral formulations: Examples of recently approved commercial products including
mini-tablets
Robert Strickley, Gilead Sciences Incorporated, USA
Neonatal drug development
Marisa Pertile, Chiesi Pharmaceutici S.p.A., Italy
Grazia Caivano, Chiesi Pharmaceutici S.p.A., Italy/p>
Challenges and opportunities of
paediatric formulations in China
Min Zhao, Queen’s University Belfast, School of Pharmacy,
United Kingdom
Intranasal benzodiazepines for epileptic
seizures: What took it so long?
Dr. Sveinbjorn Gizurarson, University of Iceland, Iceland
Focus Session Presentations
Age appropriateness of formulations
Transdermal and topical delivery in paediatrics
Begona Delgado-Charro, University of Bath,
United Kingdom
Acceptability in PIPs: Lessons learned, challenges and gut feelings
Siri Wang, Norwegian Medicines Agency, Norway
Administration Devices
Design of a precision medication dispenser:
Preventing overdose by increasing accuracy and
precision of dosage
Khalil Ramadi, Harvard-MIT Health Sciences and
Technology, USA
Review of breastfeeding mediated therapeutic
delivery
Stephen Gerrard, JustMilk, USA
Biopharm
Harmonisation of biopharmaceutics risk assessment
across regions – reflections from the ICH M9 BCS
guideline, and considerations for paediatric
biopharmaceutics
Talia Flanagan, UCB, Belgium
In vitro models to estimate oral drug solubilization in
the young pediatric population
Ragna Berthelsen, University of Copenhagen, Denmark
Excipients
Update evolving titanium dioxide situation Europe
and its potential impact
Kevin Hughes, IPEC, United Kingdom
Excipients in neonatal medicinal products: Never
prescribed, commonly administered
Kristine Valuer, Bispebjerg and Frederiksberg University
Hospitals, Copenhagen, Denmark
Taste masking and taste testing
The discovery and use of bitter taste receptor
antagonists to alleviate off-tastes
Guy Servant, Firmenich Flavors, USA
Sensory strategies and technologies to improve the
palatability of medicines
Carol Christensen, Monell Chemical Senses Center, USAdom
Innovation Show Cases Presentations
Innovation Show Cases Presentations
Device development for paediatric: Considerations for commercialization of formulation appropriate dosing devices
Alex Mills, Merck, USA
Antimalarial product development - case study
Terry Ernest, GSK, UK
Soap Box Presentations
A toolbox for simulating gastrointestinal conditions in
children: Standardised dissolution media for
stimulating typical children’s breakfasts around the
world
Lisa Freerks, University of Greifswald, Greifswald, Germany
3D printed polyethylene oxide oral doses with
innovative ‘radiator-like’ design: Impact of molecular
weight on mechanical and rheological properties and
drug release
Matthew Peak, Alder Hey Children’s NHS Foundation Trust,
Liverpool, United Kingdom
European variations in paediatric formulations
preferences: initial results of a proof of concept study
of patients research involvement via EPTRI (European
Paediatric Translational Research Infrastructure)
Francis Brako, UCL School of Pharmacy, London,
United Kingdom
Acceptability, swallowability and palatability of
oblong-tablets in young children - a randomized
controlled trial
Vivianne Klingmann, University Children’s Hospital Düsseldorf,
Düsseldorf, Germany
Development of a new age-appropriate formulation
(AaF) tool for the assessment of medicines in children
Jennifer C. Duncan, Alder Hey Children’s NHS Foundation
Trust, Liverpool, United Kingdom
Tailoring IV infusions for preterm low birth weight
neonates - the effect of vertical pump position
Kamelia Krysiak, School of Pharmacy, Royal College of
Surgeons in Ireland, Dublin, Ireland
Development of robust orally dispersible powder
formulations
Greame Macleod, SPI Pharma Inc, USA
Taste-masking and immediate release: you can have
both
Nathan Dormer, Orbis Biosciences, USA
Poster Presentations
Indian Paediatric Formulation Initiative (IPFI) – Rising to the challenge of formulating medicines for children in low resource settings
Smita Salunke, School of Pharmacy, University College London, UK
Evaluation of palatability during the development of temozolomide oral suspension for paediatric use
Melanie Hinterlang, Gustave Roussy, Villejuif, France,
Development of Robust Orally Dispersible Powder Formulations
Graeme Macleod,, SPI Pharma Inc, United States
Development of novel heteroionic alginate beads for controlled drug release: A step towards the development of personalized paediatric dosage forms
Noelia M. Sanchez-Ballester, Faculté Des Sciences Pharmaceutiques Et Biologiques, Montpellier Cedex 5
risk evaluation of gastro intestinal (gi) absorption of chloroquine (cq) in malnourished children using modelling and simulation
Gopal Pawar, School of Pharmacy, The University of Birmingham, UK.
Addressing biopharmaceutical issues in pediatric drug development: A Roche case study
Cordula Stillhart, F. Hoffmann-La Roche, Pharm R&D NCE, Basel
Development of bilayered mini-tablets for paediatric use
Ard Lura, Institute of Pharmaceutics and Biopharmaceutics, Heinrich Heine University, Düsseldorf, Germany
Dissolution of orally disintegrating mini-tablets
Sofia Mattsson, Department of Pharmacology and Clinical Neuroscience, Umeå University, Umeå, Sweden;
Gastro-resistant minitablets with pantoprazole or diclofenac for pediatric patients - optimization of fluid bed coating process
Maja Szczepanska, Department of Pharmaceutical Technology, Medical University of Gdansk, Gdansk, Poland
European variations in paediatric formulations preferences: initial results of a proof of concept study of patients research involvement via EPTRI (European Paediatric Translational Research Infrastructure)
Francis Brako, on behalf of the European
Paediatric Translational Research Infrastructure (EPTRI) project
Use of an excipient in dry form for the preparation of pediatric oral suspensions
Violaine Delannoy,
Taste-modifiers as a bitter masking strategy for children
Danielle Andrews, University College London School of Pharmacy, UK
Collective Idea Canvas: Innovation in Excipients for Pediatric Dosage Forms
Smita Salunke, On behalf of IQ and EuPFI
Development of a paediatric oral suspension of a novel drug for the treatment of kidney disease
Nazim Kanji, Quotient Sciences, Nottingham, UK;
Application of Rodent Brief-Access Taste Aversion (BATA) Model on Taste Assessment of Five MSD Market Compounds
Wei Zhu, Merck & Co., Inc, United States.
The impact of using relevant luminal fluid volumes on a PBPK model of Ritonavir absorption in children
Eleni Papadatou-Soulou, School of Pharmacy, The University of Birmingham, UK,
Preparation of Two-component Orodispersible “Tandem” Films by modified Solvent Casting Technique
Anja Göbel, Institut für Pharmazeutische Technologie und Biopharmazie
Heinrich-Heine-Universität Düsseldorf, Germany
A toolbox for simulating gastrointestinal conditions in children: Standardised dissolution media for simulating typical children's breakfasts around the world
Lisa Freerks, Institute of Biopharmaceutics and Pharmaceutical Technology, Department of Pharmacy, University of Greifswald, Germany
Relative bioavailability studies with liquids and soft foods to ensure the safe use of dosing vehicles? A critical assessment
Lisa Freerks, Institute of Biopharmaceutics and Pharmaceutical Technology, Department of Pharmacy, University of Greifswald, Germany
age-appropriate sodium valproate formulations are associated with better clinical outcomes
Hannah Batchelor, School of Pharmacy, The University of Birmingham, UK
Understanding acceptance and swallowability of bitter tasting tablets in children
Justyna Hofmanová, School of Pharmacy, The University of Birmingham, UK
Co-designing methods to assess the acceptability of medicine to children
Beth Gibson, Faculty of Health, Social Care and Medicine, Edge Hill University, Ormskirk,
Handheld device combining medicine with digital capability
Stéphane Baronnet, OnDosis AB,
Considerations for a dosing and administration device for minitablets
Tonio Raphael Hoche, F. Hoffmann-La Roche, Pharm R&D NCE, Basel
Manipulation of tablets to provide an age-appropriate dose: Do we get the right dose?.
Ingunn Tho, Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Oslo, Norway
Acceptability study in a Moroccan hospital: tablets use and misuse
Thibault Vallet, ClinSearch, Malakoff, France
Acceptability, Swallowability, and Palatability of Oblong-tablets in Young Children – A Randomized Controlled Trial
Juliane Münch, Department of General Paediatrics and Neonatology, University Children‘s Hospital, Düsseldorf, Germany
A retrospective survey of compounded medicines for children in Japan
Jumpei Saito, Department of Pharmacy, National Center for Child Health and Development (NCCHD), Okura 2-10-1, Setagaya-ku, Tokyo, Japan.
3D printed Polyethylene Oxide oral doses with innovative ‘radiator-like’ design: Impact of molecular weight on mechanical and rheological properties and drug release
Matthew Peak, Alder Hey Children's NHS Foundation Trust,Liverpool, UK
Taste evaluation of three different commercial tablets for paediatric patients for neglected tropical diseases
Janine Boniatti, Laboratório de Farmacotécnica Experimental (LabFe), Rua Sizenando Nabuco, 100. Manguinhos, RJ.
EPTRI - European Paediatric Translational Research Infrastructure: turning the spotlight on paediatric formulations advancement
Valeria Pignataro, Consorzio per Valutazioni Biologiche e Farmacologiche, Via Nicolò Putignani, BARI.
Development of a new Age-appropriate Formulation (AaF) tool for the assessment of medicines in children
Jennifer C Duncan, Paediatric Medicines Research Unit, Alder Hey Children’s NHS Foundation Trust, Liverpool, United Kingdom
Tailoring IV infusions for preterm low birth weight neonates – the effect of vertical pump position
Kamelia Krysiak, School of Pharmacy, Royal College of Surgeons in Ireland, Dublin.
Human Factor Study Demonstrates Reduced Dosing Errors for Novel Color-Coded Delivery System for Epinephrine to Treat Anaphylactic Reactions in Children
Daniel Schaufelberger, Schaufelberger Consulting LLC
Manipulating medicines for children: a comparison of skills between undergraduate pharmacy; nursing and medical students
Ahmed Abdullah Lahiq, School of Pharmacy, Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, United Kingdom
Challenges to develop a liquid pediatric matching placebo for blinding in controlled randomized clinical trials
Carsten Timpe, F. Hoffmann La Roche AG, Basel
Development of Oral Liquid Products for Neonatal Patients
Kingsley Iyoha, Quotient Sciences,Mere Way, Ruddington, Nottingham, United kingdom
Creating Acceptable Tablets 3D (CAT 3D): A feasibility study to evaluate the mouthfeel of 3D printed tablets in children and young people.
Louise Bracken, Paediatric Medicines Research Unit, Alder Hey Children’s NHS Foundation Trust, Liverpool, United kingdom
Manipulations of dosage forms on paediatric wards of a German university hospital – an underestimated problem?
Julia Zahn, Universitätsklinikum Erlangen, Department of Paediatrics and Adolescent Medicine, Paediatric Clinical Study Centre, Loschgestraße, Erlangen
COLLECTIVE IDEA CANVAS: Innovation in Excipients for Pediatric Dosage Forms
John Alexander, FDA/CDER, Silver Spring, MD, USA
Three Best Poster Award Winners:
Young Scientist Award Winner:
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