3rd EuPFI Conference, Strasbourg

Welcome Message

The Organizing Committee and the Scientific Committee are pleased to announce that we have decided to post presentations from plenary, thematic and oral soap box sessions of the 3rd Conference of the European Paediatric Formulation Initiative (EuPFI) that was held in Strasbourg, France on 21st -22nd September, 2011 on our website.

By clicking on READ MORE the EuPFI members and conference participants can view and browse all PowerPoint presentations shared by speakers.

We would like to thank the speakers for their valuable support in making this possible.

Best regards,

Dr Catherine Tuleu Prof Jörg Breitkreutz

Chair EuPFI President APV

Focus Session: Extemporaneous preparations

Chair:

Terry Ernest, PhD

Principal scientist, GlaxoSmithKline, United Kingdom

Extemporaneous compounding in Europe

Maria Carvalho, PhD

School of Pharmacy, University of London, United Kingdom

International initiatives on extemporaneous dispensing(WHO, Commonwealth Pharmacy Association)

Prof. Anthony J. Nunn

NIHR Medicines for Children Research Network and Liverpool John Moores University, United Kingdom

Focus Session: Taste masking and Taste assessment

Chair:

Catherine Tuleu, PhD, Chair of EuPFI

The School of Pharmacy, University of London, United Kingdom

Assessing taste without using humans: Rat Brief ExposureAversion model and electronic tongue

David Clapham, BPh arm MRPharmS

GlaxoSmithKline, United Kingdom

Palatability assessment: an industrial perspective

Gesine Winzenburg, PhD

Novartis Pharma AG, Switzerland

Focus Session: Administration Devices

Chair:

Jenny Walsh, PhD

AstraZeneca, United Kingdom

Regulatory aspects of devices

Herbert Wachtel, PhD

Boehringer Ingelheim Pharma GmbH & Co. KG,

Germany

Development of child-appropriate devices

Dominik Erhard, PhD

Raumedic, Germany

Focus Session: Age-appropriate formulations

Chair:

Richard Kendall, PhD

MSD, United Kingdom

Off-patent Oral Oncology Drugs for Kids (O3K FP7-project): from bedside to PUMA

Dr Angelo Paci, PharmD, PhD

Institut de Cancérologie Gustave Roussy, France

Current administration practices and preferred formulations of children’s medicines in Tanzania

Dr Lisa V. Adams, M. D.

Dartmouth Medical School, United States

Focus Session: Excipients

Chair:

Prof. Jörg Breitkreutz, PhD

Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany

Excipient toxicokinetics

Karel Allegaert, PhD

Leuven University, Belgium

Update on the STEP (Safety and Toxicity of Excipient for Paediatrics) Database

Smita Salunke, MPharm

EuPFI, United Kingdom

Barbara Brandys

NIH Library, United States

Soap Box Session 1 - Wednesday, 21st September 2011

Micro Tablet Dosing Dispenser - Needs, Challenges and First Solutions

Dr. Rolf Eilers, Balda Medical GmbH & Co. KG, Germany

In vitro performance of a dry powder inhaler using mouth-throat models of 4-5-year-old children

Below, Antje et. al., Heinrich-Heine University, Institute of Pharmaceutics and Biopharmaceutics, Düsseldorf, Germany

Orodispersible Minitablets as a child-appropriate dosage form with enalapril maleate : Avoiding the problems of extemporaneous formulations?

Hermes, Martin et. al., Heinrich-Heine University, Institute of Pharmaceutics and Biopharmaceutics, Düsseldorf, Germany

Selecting the food matrix with the highest masking power for delivering recommendations for children

Morel, Sylvain et. al., Alpha MOS, Toulouse, France

Compatibility Of Y- Site Administration Of Medications With A Standard 3-In-1 Parenteral Nutrition Admixture for Paediatrics

Ingunn, Tho et. al., University of Tromsoe, Tromsoe, Norway

complete="true">Soap Box Session 2 - Thursday, 22nd September 2011

Development of Clonidine HCL Orodispersible Film For Paediatric Population

Danso Fady et. al., London School of Pharmacy, London, United Kingdom

Flavoring Of Commercial Oral Liquid Pharmaceutical Products

Embrechts, Roger et. al., Janssen pharmaceuticals, Beerse, Belgium

Steady state pharmacokinetics of the novel AZT/3TC FDC tablets in HIV-infected children

Kayitare Egide et. al., University of Ghent, Ghent, Belgium

Development and Evaluation Using Electronic Tongue of Taste-Masked Drug for Paediatric Medicines

Thanh Huong, Hoang Thi et. al., University Lille Nord, Lille, France

Acceptance of drug-free minitablets in young children

Spomer, Natalie et. al., University Children’s Hospital, Düsseldorf, Germany

The EMA Perspective: Case studies from the PDCO Formulations Group (chemicals & biologicals)

Caroline Le Barbier, PhD Scientific Administrator, Quality Sector, Chemicals, European Medicine Agency (EMA), United Kingdom Isabel Esteve, PharmD, Scientific Administrator, Quality Sector, Biologicals, European, Medicine Agency (EMA), United Kingdom

Industry case studies: Exploring a risk management approach towards developing the optimal paediatric formulation-applying quality by design and multi-criteria decision making

Tom Sam, PhD, MBM, FFIP , Director Pharmaceutical CMC, Global Quality Merck Sharp & Dohme, IP President / Science & Technology Officer, FIP’s, Industrial Pharmacy Section, United Kingdom

EMA Guideline on pharmaceutical development of medicines for paediatric use

Diana Van Riet-Nales, PharmD, Coordinator regulatory affairs, Chemical Pharmaceutical Assessment (CFB) at the Dutch National Institute for Public Health and the Environment (RIVM) and Vice-Chair of the EMA / CHMP’s Quality Working Party, The Netherlands

WHO guideline development of paediatric medicines: points to consider in pharmaceutical development

Professor Emeritus Henning Kristensen, PhD, DSc., D.hc Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, University of Copenhagen and WHO representative

FDA: Contribution to developing paediatric formulations and transatlantic collaboration